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Congressional hearings demonstrate bipartisan support for research funding
Congressional hearings demonstrate bipartisan support for research funding
Two recent House Appropriations Committee hearings on the fiscal year (FY) 2017 budget requests for the National Institutes of Health (NIH) and the National Science Foundation (NSF) demonstrated bipartisan support for the nation�s research agencies. Th...
NSF places two biological infrastructure programs on hiatus
NSF places two biological infrastructure programs on hiatus
The National Science Foundation (NSF) placed two programs that fund biological infrastructure on hiatus for evaluation. NSF will not accept proposals for its Collections in Support of Biological Research (CSBR) and Instrument Development for Biological...
Exercise may have therapeutic potential for expediting muscle repair in older populations
Exercise may have therapeutic potential for expediting muscle repair in older populations
Here's another reason why you should hit the gym regularly as you grow older: A new report appearing online in The FASEB Journal shows that regular exercise plays a critical role in helping muscles repair themselves as quickly as possible after injury....
Sign-on Letter Supports Model Organism Databases
Sign-on Letter Supports Model Organism Databases
More than 8,500 researchers have signed a letter asking the National Institutes of Health (NIH) to reconsider plans to reduce funding for model-organism databases (MODs). In May, the National Human Genome Research Institute informed investigators leadi...
Senate committee completes consideration of medical innovation legislation
Senate committee completes consideration of medical innovation legislation
The Senate Health, Education, Labor & Pensions (HELP) Committee took another step forward in their ongoing effort to advance legislation similar to the 21st Century Cures bill that was passed by the House last year. On April 6, the�HELP Committee appro...
Traveling through space? Don't forget your sleeping pills and skin cream
Traveling through space? Don't forget your sleeping pills and skin cream
If you are planning to take the long trip to Mars, don't forget to pack sleeping pills and skin cream. A new study published in the November 2015 issue of the FASEB Journal, is the first-ever examination of the medications used by astronauts on long-du...
HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus
HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus
P2X7 receptors (P2X7Rs) are ATP-gated ion channels that display the unusual property of current facilitation during long applications of agonists. Here we show that facilitation disappears in chimeric P2X7Rs containing the C-terminus of the P2X2 recept...
NIH Advisory Committee Discusses Initiatives to Improve Diversity and Data Sharing
NIH Advisory Committee Discusses Initiatives to Improve Diversity and Data Sharing
Initiatives to improve diversity and increase data sharing dominated the 112th�meeting of the National Institutes of Health (NIH) Advisory Committee to the Director (ACD) on June 9 and 10. Hannah A. Valantine, MD, NIH Chief Officer for Scientific Workf...
Researchers suggest playing American Football may be a risk factor for hypertension
Researchers suggest playing American Football may be a risk factor for hypertension
As National Football League playoff games are underway, a new article published in the "Hypotheses" section of the January 2016 issue of The FASEB Journal, suggests that the toll the sport takes on players' bodies extends beyond head trauma and damage ...
Senate Committee Approves Bill to Expand Opportunities for Young Researchers
Senate Committee Approves Bill to Expand Opportunities for Young Researchers
Legislation to improve career opportunities for young researchers moved forward last week as the Senate Health, Education, Labor and Pensions (HELP) Committee unanimously approved the Next Generation Researchers Act (S 2014) co-authored by Senators Tam...
Ten Simple Rules for Effective Statistical Practice
Ten Simple Rules for Effective Statistical Practice
Several months ago, Phil Bourne, the initiator and frequent author of the wildly successful and incredibly useful �Ten Simple Rules� series, suggested that some statisticians put together a Ten Simple Rules article related to statistics.
Plant hormone may play a vital role in blood sugar control and diabetes management
Plant hormone may play a vital role in blood sugar control and diabetes management
A treatment for managing blood sugar levels might be as close as the local health food store, suggests a new research report published in the December 2015 issue of The FASEB Journal. Specifically scientists from Italy have found that when the plant an...
NIH Releases Final Policy on Use of Single IRBs for Multi-site Studies
NIH Releases Final Policy on Use of Single IRBs for Multi-site Studies
On June 21, the National Institutes of Health (NIH) issued its final policy on the use of single Institutional Review Boards (IRBs) for multi-site research studies and clinical trials. The policy �establish(es) the expectation that a single IRB of reco...
Blind analysis: Hide results to seek the truth
Blind analysis: Hide results to seek the truth
Decades ago, physicists including Richard Feynman noticed something worrying. New estimates of basic physical constants were often closer to published values than would be expected given standard errors of measurement1. They realized that researchers w...
Eating Soy May Protect Women from Health Risks of BPA
Eating Soy May Protect Women from Health Risks of BPA
Consuming soy regularly may protect women who are undergoing infertility treatments from poor success rates linked to bisphenol A exposure, according to a new study published in the Endocrine Society�s Journal of Clinical Endocrinology & Metabolism.
NIH Office of Research Infrastructure Programs Releases Strategic Plan
NIH Office of Research Infrastructure Programs Releases Strategic Plan
The Office of Research Infrastructure Programs (ORIP) at the National Institutes of Health (NIH) recently released its 2016-2020 Strategic Plan. ORIP�s mission is to support trans-NIH research infrastructure and resource programs and to coordinate NIH�...
NSF report shows growth in global R&D spending
NSF report shows growth in global R&D spending
On February 1, the National Science Board (NSB) announced the release of the 2016 Science and Engineering Indicators (SEI) report at a briefing on Capitol Hill. The report, which is updated every two years, details the state of the nation�s scientific ...
Research Resources for Nuclear Receptor Signaling Pathways
Research Resources for Nuclear Receptor Signaling Pathways
Nuclear receptor (NR) signaling pathways impact cellular function in a broad variety of tissues in both normal physiology and disease states.
Baxter Family Gifts $1.2 Million to Endocrine Society to Recognize Innovation and Entrepreneurshi...
Baxter Family Gifts $1.2 Million to Endocrine Society to Recognize Innovation and Entrepreneurshi...
With a $1.2 million gift from the family of Dr. John D. Baxter, the Endocrine Society today established the John D. Baxter Prize for Entrepreneurship to recognize scientists and clinicians who have demonstrated innovation and entrepreneurship by furthe...
NIH releases strategies for communicating research
NIH releases strategies for communicating research
The National Institutes of Health (NIH) released a list of strategies to help scientists make their research more accessible to the broader public. The guidelines, which include tips for researchers, educators, journalists, and other health professiona...
Comparison of (+)- and (?)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Ace...
Comparison of (+)- and (?)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Ace...
Toll-like receptor 4 (TLR4) signaling is implied in opioid reinforcement, reward, and withdrawal. Here, we explored whether TLR4 signaling is involved in the acute psychomotor-stimulating effects of heroin, 6-acetylmorphine (6-AM), and morphine as well...
Number of postdocs declines for first time, new FASEB journal study shows
Number of postdocs declines for first time, new FASEB journal study shows
After more than 30 years of steady growth, the number of postdocs in the biological and biomedical sciences is on the decline in the United States, according to a new paper in The FASEB Journal. The study shows that despite continuing increases in the ...
House Passes Controversial NSF Grant Certification Bill
House Passes Controversial NSF Grant Certification Bill
On February 10, the House of Representatives passed Scientific Research in the National Interest Act (H.R. 3293) by margin of 236-178 along a nearly party-line vote. The bill would place new, stricter requirements on the grant-making processes at the N...
FY2017 Labor, HHS & Education Appropriations Bill Cleared for Senate Consideration
FY2017 Labor, HHS & Education Appropriations Bill Cleared for Senate Consideration
The Senate Committee on Appropriations today approved for Senate consideration a bipartisan spending bill that provides increased funding for medical research, job training, educational opportunities and the fight against opioid abuse.
FASEB Supports Legislation to Reduce Regulatory Burden
FASEB Supports Legislation to Reduce Regulatory Burden
The Federation of American Societies for Experimental Biology (FASEB) endorsed legislation introduced on June 24 by Representative Daniel Lipinski (D-IL) entitled the University Regulation Streamlining and Harmonization Act of 2016. In a letter to Cong...
FASEB Identifies Ways to Reduce Burden at USDA
FASEB Identifies Ways to Reduce Burden at USDA
On May 5, the Federation of American Societies for Experimental Biology (FASEB) responded to a Request for Information (RFI) issued by the United States Department of Agriculture (USDA) on identifying and reducing regulatory burdens. The RFI sought fee...
Hearing Raises Concerns About Diverting Research Funds to Small Business Grants
Hearing Raises Concerns About Diverting Research Funds to Small Business Grants
A June 16 hearing of the House Science, Space and Technology Subcommittee on Research and Technology raised concerns about the reauthorization of Small Business Innovation Research (SBIR) and the Small Business Technology Transfer (STTR) programs. Alth...
Mechanisms of Action of Novel Influenza A/M2 Viroporin Inhibitors Derived from Hexamethylene Amil...
Mechanisms of Action of Novel Influenza A/M2 Viroporin Inhibitors Derived from Hexamethylene Amil...
The increasing prevalence of influenza viruses with resistance to approved antivirals highlights the need for new anti-influenza therapeutics. Here we describe the functional properties of hexamethylene amiloride (HMA)�derived compounds that inhibit th...
Latonduine Analogs Restore F508del�Cystic Fibrosis Transmembrane Conductance Regulator Traffickin...
Latonduine Analogs Restore F508del�Cystic Fibrosis Transmembrane Conductance Regulator Traffickin...
Cystic fibrosis (CF) is a major lethal genetic disease caused by mutations in the CF transmembrane conductance regulator gene (CFTR). This encodes a chloride ion channel on the apical surface of epithelial cells. The most common mutation in CFTR (F508d...
Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease
Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease
The autophagy pathway has been recognized as a mechanism of survival and therapy resistance in cancer, yet the extent of autophagy�s function in metastatic progression is still unclear. Therefore, we used murine models of metastatic cancer to investiga...
National Academies Committee Calls for New Review of Human Subjects Research
National Academies Committee Calls for New Review of Human Subjects Research
On June 29, the National Academies of Science, Engineering, and Medicine released the final version of �Optimizing the Nation�s Investment in Academic Research: A New Regulatory Framework for the 21st Century.� The Academies report calls for the creati...
Magnesium ions show promise in slowing progression of Alzheimer's disease in mice
Magnesium ions show promise in slowing progression of Alzheimer's disease in mice
New research published in the December 2015 issue of The FASEB Journal, shows that in mouse models of the disease oral administration of magnesium-L-threonate (MgT) alleviated cognitive decline by suppressing the A? deposition in amyloid plaques in an ...
FASEB endorses bill to strengthen privacy protections for research participants
FASEB endorses bill to strengthen privacy protections for research participants
On July 5, the Federation of American Societies for Experimental Biology (FASEB) endorsed U.S. Senate bill S.2744, the �Genetic Research Privacy Protection Act,� which aims to enhance privacy protections for research participants. The bill would streng...
Fair Pay for Postdocs: Why We Support New Federal Overtime Rules
Fair Pay for Postdocs: Why We Support New Federal Overtime Rules
The Department of Labor�s recently announced revisions to the Fair Labor Standards Act (FLSA) will make more than 4 million currently exempt U.S. workers eligible for overtime pay, unless their salaries are raised.
President Obama prioritizes medical research
President Obama prioritizes medical research
The Federation of American Societies for Experimental Biology (FASEB) thanks President Barack Obama for his support for federal investment in biomedical research in his final State of the Union address.
FASEB welcomes new president and officers
FASEB welcomes new president and officers
On July 1, the Federation of American Societies for Experimental Biology (FASEB) welcomed its new President, Hudson H. Freeze, PhD.�Dr. Freeze is Professor of Glycobiology and Director of the Human Genetics Program at the Sanford-Burnham-Prebys Medical...